Pru p 9, a new allergen eliciting respiratory symptoms in subjects sensitized to peach tree pollen
نویسندگان
چکیده
منابع مشابه
Severe peach allergy in patients non-sensitized to Pru p 3
Background Allergy to Rosaceae is the fourth leading cause of food allergy in children in France. Typically, in Northern Europe, there is a prior sensitization to birch, through a PR-10 protein, while in Southern Europe the allergy is often preceded by a sensitization to a Lipid Transfer Protein (LTP). In Spain it is often recorded as a subsequent sensitization to apple (cross-reaction between ...
متن کاملPru p 3-sensitised Italian peach-allergic patients are less likely to develop severe symptoms when also presenting IgE antibodies to Pru p 1 and Pru p 4.
BACKGROUND The roles played by different peach allergens with respect to symptom severity have not been completely ascertained. We have evaluated the diagnostic efficacy of peach recombinant allergens ImmunoCAP compared to peach in the identification of subjects at an increased risk for severe reactions to peaches. METHODS 148 peach-allergic patients were divided based on their symptom severi...
متن کاملHypoallergenic allergen derivatives of Pru p 3 for immunotherapy of IgE-mediated peach allergy
Background IgE-mediated allergy to peach represents a frequent cause of severe anaphylactic reactions in Mediterranean countries. Pru p 3, a nonspecific lipid transfer protein (LTP) from peach, was identified as an important elicitor of IgEmediated food hypersensitivity reactions to peach. Specific immunotherapy is currently the only allergen-specific and disease-modifying treatment of allergie...
متن کاملT-cell epitopes of the major peach allergen, Pru p 3: Identification and differential T-cell response of peach-allergic and non-allergic subjects.
Lipid transfer proteins (LTPs), particularly peach Pru p 3, are the most relevant plant food allergens in the South of Europe, and, therefore, their allergic properties have been extensively studied. However, neither T-cell epitopes nor their effect on the patients' T-cell response has been investigated in any member of the LTP panallergen family. The objective of the present study was to map t...
متن کاملPeach allergy: different clinical profiles across Europe
Rosaceae fruit allergy is the most common food allergy in Europe in patients over 5 years of age. The two fruits most frequently involved are peach and apple. Different clinical phenotypes of peach allergy are observed across Europe in relation to different allergen sensitisation patterns to the peach allergens Pru p1 (Bet v 1 homologue), Pru p 3 (peach lipid transfer protein, LTP), and Pru p 4...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: PLOS ONE
سال: 2020
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0230010